Ghazala Butt, Ejaz Hussain, Abdur Rehman.
Comparative Analysis of Antioxidant Potential of Sargassum Sp and Lyengaria Sp.
Pak J Med Health Sci Jan ;7(4):1128-9.

Aim: To evaluate wide ranging bioactive ingredients using in-vitro assays for a better understanding of the protein networks which are targeted by natural agents. Methods: Sargassum sp and Iyengaria sp were collected from southeast coast of Karachi. The powdered seaweed samples (500 g of Sargassum sp and Iyengaria sp) were extracted with methanol in conical flasks at room temperature for three weeks. The samples were filtered using Whatman filter paper to obtain clarified filtrates. ABTS radical scavenging assay and FRAP assays were used to analyze antioxidant potential. Results: The methanolic extract of Sargassum sp showed higher potential of antioxidant activity as evidenced by ABTS radical scavenging assay. Methanolic extract of Iyengaria sp show the highest FRAP value 26.5 mM, indicating to highest antioxidant potential as evidenced by FRAP assay. Conclusion: Identification of bioactive ingredients having considerable antioxidant potential will be helpful in better and deeper understanding of the underlying mechanisms inhibited or activated by natural agents to suppress carcinogenesis.

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