Bushera Sher Zaman, Salma Jabeen, Jaweria Rashid.
Frequency of Positive Endometrial Pipelle Biopsies in for Detection of Endometrial Carcinoma in patients of Civil Hospital with Abnormal Uterine Bleeding.
Pak J Med Health Sci Jan ;7(3):743-7.
Aim: The objective of this study was to determine frequency of positive endometrial biopsies in pre and post menopausal patients with abnormal uterine bleeding for detection of endometrial carcinoma Study design: Cross-sectional study Settings: Gynecological outpatient department Civil Hospital Bahawalpur. Methods: Pre and post-menopausal women between 35-70 years with abnormal uterine bleeding fulfilling inclusion and exclusion criteria were selected for the study. After detailed history and examination, informed consent, pipelle endometrial biopsy was taken. Biopsy of each patient was labeled and sent to the histopathology department of Bahawal Victoria Hospital Baawalpur for histopathology. The biopsy was deemed as positive if it detects endometrial carcinoma on histopathology and vice versa. Data was analyzed by using SPSS version 10. Descriptive statistics were used to analyze the data. Results: Among 126 patients, majority (38.09%) were in age group 35-45 years and were multipara. 58.73% patients were post-menopausal and menorrhagia was the most frequent presenting complaint. Amount of tissue obtained on curetting with Pipelle was adequate in 96.82% of cases. The most frequent histopathology finding on pipelle endometrial sampling was secretary endometrium i.e. in 38.88% of cases. Endometrial biopsy for carcinoma was positive in only 5.55% of cases. Conclusion: Pipelle biopsy is definitely a useful and cost-effective method. It can reduce the number of D &Cs performed in the operating theatre. The accuracy of the Pipelle is higher in postmenopausal women compared with premenopausal women.
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