Shafique Ahmed, Shehzad Ahmad, Anwar-ul Hasan.
Use of Statins in Unstable Angina and their Effect on Recurrent Hospital Admissions.
Pak J Med Health Sci Jan ;7(1):216-8.

Objective: To determine the effect of lipid lowering with the use of statins on recurrent anginal symptoms. Study design: Case-control type of study. Place and duration: The study was conducted in the department of Cardiology, Bahawal Victoria Hospital Bahawalpur from 15th March 2010 to 15th March 2012. Methodology: During the initial one year of study, patients fulfilling the inclusion criteria were registered. The data regarding the age at the time of presentation, gender, co-morbidities (diabetes mellitus, hypertension, smoking, BMI), baseline lipid levels and drugs taken for symptomatic coronary artery disease was collected on a predesigned proforma. Lipid lowering therapy was optimized in those patients who were having deranged lipid profile. During the second year of study, the data regarding frequency of anginal symptoms and hospital admissions was collected and the relation between serum lipid levels and recurrent hospital admissions was determined. Results: A total of 1206 patients met the inclusion criteria of the study, 594 having normal lipid levels (group A) and 612 having deranged serum lipid profile (group B). It was found that during the one year follow up time, 99 patients in group B required recurrent hospital admissions for symptomatic angina as compared to 36 in group A, and this difference was statistically found to be significant. Conclusion: The patients who are having normal lipid levels need a significantly less number of admissions for symptomatic angina as compared to those who are having deranged lipid levels.

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