Iftikhar Hussain, Salman Ahmad, Muhammad Zaman, Muhammad Aqeel, Samra Y Haq, Kashif Zafar.
In hospital mortality among patients with high platelet /lymphocyte ratio presenting with ST segment elevation myocardial infarction.
J Cardiovascular Dis Jan ;14(4):100-3.

BACKGROUND: Increased platelet activation with increased platelet count and reduction in lymphocyte count (platelet to lymphocyte ratio) is recognized as a marker of inflammation and is linked with adverse cardiovascular events. The objective of this study was to determine in- hospital mortality among patients suffering from ST elevation myocardial infarction (STEMI) and having high platelet to lymphocyte ratio . MATERIAL AND METHODS: We did this study in Punjab institute of cardiology, Lahore from 0ct 19, 2015 to April 18, 2016. One hundred and twenty patients having high platelet/lymphocyte ratio (>144) were enrolled. Absolute platelet and lymphocyte counts were calculated and platelet to lymphocyte ratios derived. The enrolled patients were followed during their hospital stay for mortality. RESULTS: A total of 120 patients were studied. Mean age of the study population was 44.9 + 8.3 years and 85 (70.8%) were males. Overall 15 (12.5%) patients died in hospital. Out of those who died, 9 were male and 6 were female. There was a non significant trend for higher mortality in women with high platelet / Lymphocyte ratio; 17.1% vs 10.6 % (p valve 0.367). CONCLUSION: A mortality of 12.5% was observed among patients suffering from STEMI and having high platelet to lymphocyte ratio. KEY WORDS: Platelet to lymphocyte ratio, ST elevation myocardial infarction, In-hospital mortality

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