Muhammad Younas, Ahsan Beg.
Patent ductus arteriosus device occlusion in young children less than 12 kg - immediate results and complications.
Pak Heart J Jan ;47(4):193-7.

Objective: To assess the immediate results and complications of transcatheter closure of patent ductus arteriosus (PDA) in young children less than 12kg of weight. Methodology: This descriptive cross-sectional study was conducted at department of Paediatric Cardiology, Chaudhry Pervaiz Elahi Institute of Cardiology, Multan from September 2009 to October 2013. Patients who under went PDA closure for moderate to large PDA with LV volume overload without severe pulmonary hypertension who were <12kg were included. Pre and Post Procedure Echocardiography was performed. Complications of procedure including mortality were recorded. Results: A total of 123 patients underwent PDA occlusion of which 44 (36%) patients were <12kg. Mean age was 2+-1.034 and weight was 9.5kg +- 1.88. Procedure was successful in all patients without any mortality or major complications. Small residual PDA in Cath Lab was present in 03 (6.8%), which resolved in 24 hours. Loss of arterial pulse was present in 08(18%) patients which recovered within 24 hours with heparin infusion. Protrusion of aortic end of device without aortic obstruction was present in 10(23%) patients. Partial LPA obstruction due to device (Echo gradient between 15-30mmHg) was present in 04(09%) patients. There was no device embolization. Conclusion: Percutaneous closure of moderate to large PDA in young children weight less than 12kg is a safe procedure without major complications. Loss of arterial pulse, protrusion of aortic end of device without aortic obstruction, partial LPA occlusion and residual PDA were the common immediate post device implantation complications.

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