Shazia Shaheen, Sumara Tahir.
Management and outcome of severe pre-eclampsia.
Annals Punjab Med Coll Jan ;2(1):30-4.

Objectives: To know how frequent this problem is encountered in our hospitals and to evaluate fetomaternal outcome by adopting a specific management protocol. Design: This was a prospective observational study. Setting: The study was carried out in Labour Ward of Gyneacology and Obstetrics Units-II, Punjab Medical College, D.H.Q. Hospital Faisalabad from 1st January 2000 to 31st December 2000. Material & Method: Forty one pregnant women diagnosed as having severe pre-eclampsia were managed according to severity of disease and duration of pregnancy. After 34 weeks stabilization and delivery, in patients presenting before 26 weeks termination of pregnancy   and   for   those   between 26 to 34  weeks expectant management  was done,  using antihypertensives to control blood pressure, corticosteroids for fetal lung maturity and serial fetomaternal evaluation. Results: Frequency of occurrence of pre-eclampsia was found to be 1.55%. Most patients were between 20-25 (44%) years of age and primigravidas were most afflicted (48.8%). Eclampsia (2%) abruption (32%) acute renal failure (32%) HELLP Syndrome (8%) were the associated maternal complications. Maternal mortality was 4.*% and perinatal morality was 30%. Conclusions: Severe pre-eclampsia continues to present as one of leading causes of maternal morbidity perinatal and mortality. Improvement of antenatal care, early recognition and prompt intervention can reduce the bad outcome.

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