Ayesha Khalil, Shazia Hafiz, Asif Iqbal, Rahema Aman, Hina Iqbal, Ayesha Zafar, Adnan Mahmood Gul.
Effect of psychotherapy on depressed patients with coronary artery disease (CAD).
Pak Heart J Jan ;51(4):342-6.

Objectives: To see the effects of psychotherapy in depressed patients with coronary artery disease (CAD) Methodology: This was a randomized clinical trial conducted in Preventive section, Cardiology department, Lady Reading Hospital, Peshawar from March 2018 to October 2018. Verbal informed consent was taken from patients. Patients from both genders and all ages were included. Patients were randomly allocated to therapy group and non-therapy group. In therapy group, treatment plan based on cognitive behavioral therapy techniques, were administered to subjects. There were six session in total, two every week. The subjects in non therapy group received routine care. After completing the sessions, the subjects were reassessed by PHQ-9 to see improvement in the level of depression. Datais presented as frequency, mean and standard deviation calculated for each variable. Paired T test was used to compare continuous data and Chi-square for categorical variables. Results: A total of 1100 patients with CAD presenting to cardiology department were enrolled. Out of these 1100 patients, 272 post MI patients diagnosed with of depression on PHQ- 9 were selected for the study.. A sample of 260 subjects who met the inclusion criteria was analyzed Therapy group had 125 subjects and non-therapy group had 135 subjects. Mean age was 57.07+-13.07. Males were 43% and females 57%. Of total literate were 33%, hypertension was documented in 52.3 %, diabetes in 31.2%, and Current smokers were 21.2 %. At baseline the PHQ scores were 10.08+-1.68 in therapy group and 10.10+-1.49 in non-therapy group respectively (p =0.783). After six sessions of treatment, therapy group showed reduction in level of depression PHQ-9 scores to 6.04+-0.347 PHQ scores were 10.08+-1.68 in therapy group and 10.10+-1.49 in non-therapy group (p 0.783) at the baseline (p<=0.001), In non therapy group the level of depression did not reduce significantly. Conclusion: Psychotherapy was found to be effective treatment in reducing symptoms of depression.

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