Maryam Bashir, Shafqat Mukhtar, Muhammad Ikram, Amna Javed.
Vitamin D deficiency and PCOS; association between vitamin D deficiency and PCOS in females presenting in a tertiary care hospital..
Professional Med J Jan ;26(01):40-4.

Background: Polycystic ovary syndrome (PCOS) is mainstream gynaecological problems in adult women. Vitamin D has been linked to propensity of developing PCO. As this hormones has certain effects on insulin sensitivity and restoration of reproductive capacity in women with PCOs. So, a study was planned to establish correlation of deficiency of vitamin D and PCOs. Objective To determine the correlation of deficiency of vitamin D with PCOs in patients reporting to a teaching hospital. Material & Methods : Case control study carried out at institute of Shaikh Zayed Hospital, Lahore, Gynae-Obst Department for six months. If serum level of vitamin D is < 25nmol/L then deficiency was labeled. Odds ratio was calculated between PCOs and vitamin D deficiency, Results: The mean age of the patients was 26.91±6.09 years. In this study, 70% females were married. The mean BMI of patients was 22.59±2.48kg/m2, and 76(76%) patients had normal BMI and 24(24%) patients were overweight. Vitamin D deficiency was observed in 47 cases in which 31 were from case group and 16 were from control group with significant association i.e. OR=3.47. Conclusion: Our study results concluded that there is more risk of vitamin D deficiency in females with PCOS as compared to females without PCOS.

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