Mahnoor Mohydin, Mohammad Haroon-ur Rasheed, Amna Kamran, Hashim Hayat, Aeman Nisar, Mischa Sheikh, Ayesha Ehsan, Muhammad Zain Raza, Muhammad Abdul Samad, Faiza Bashir.
Culture and Sensitivity pattern of Urinary Tract Infections among Women of Reproductive age group.
Pak J Med Health Sci Jan ;13(2):263-6.

Aim: To identify the culture and sensitivity pattern of microorganisms in urinary tract infection ( UTI ) among women of reproductive age group . Methods: A retrospective study was conducted in the Microbiology department, Services Institute of Medical Sciences, where patient’s records of all positive culture for UTI during the one year period from November, 2017 to October 2018 were retrieved. The inclusion criteria were; patients with confirmed diagnosis of UTI, women with age 18 to 44 years and culture positivity. Patients with history of prior antibiotic therapy, incomplete records, recent surgery and steroid therapy were excluded. The freshly voided midstream urine samples were analyzed for urine culture and Antibiotic Sensitivity Test (ABS). The research was initiated after the ethical approval was granted by the Institutional Review Board (IRB) of Services Institute of Medical Sciences, Lahore. Results : The records of 96 urine samples from females of reproductive age were analyzed for isolation of the bacterial isolates. The age range was 18 to 44 years with mean (SD) as 28.54 (7.63) years. The most common urinary tract pathogen identified was Escheraec ia coli (49%), followed by Staphylococcus Aureus (24%), Klebsiella pneumoniae (17.7%) and Enterobacter spp. (4.2%). There were sixty six (68.8%) females having severe UTI infection. Against E. coli highest sensitivity was observed for Meropenem (100%), Fos fomycin (100%), Nitrofurantoin (100%), Imipenim (97.9%), Amikacin (91.5%) and Cefaparazone/ Sulbactam (72.3%). Moreover, against Staphylococcus Aureus highest antibiotics sensitivity was identified for Imipenim (95.7%), Meropenem (95.7%), Tetracycline (91. 3%), Cefaparazone/ Sulbactam (87%), Augmentin (87%) and Nitrofurantoin (78.3%), Conclusion: Most common urinary tract pathogens in females of reproductive age group were E. coli and Staphylococcus Aureus. Meropenem, Fosfomycin, Nitrofurantoin, Imipenim and Amikacin were the most effective antibiotics against E. coli. However, against Staphylococcus Aureus the most sensitive antibiotics were identified as Imipenim, Meropenem and Tetracycline.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com