Sikandar Javed Bajwa, Malik Arshman Khan, Muhammad Usman Muneer.
Use of Inductive Coupled Plasma Mass Spectroscopy to Analyze the Properties of Ions Released by Bioactive Glasses and Bone Scaffolds.
Pak J Med Health Sci Jan ;12(1):2-5.

This research discussed the characterization, fabrication and in vitro study of bone scaffolds and bioactive glasses. Bioactive glass is a novel material that dissolves and forms a bond with bone when exposed to body fluids. Bioactive glasses are silicate based, having calcium and phosphorous in equal ratio to those of the natural bone and this is the reason for their high biocompatibility. Traditionally bioactive glasses have been used to restore bone defects. The bioactive bone scaffolds have been discussed on the basis of melt derived bioactive silicate glass compositions. In addition ion release effects of bioactive glasses and scaffolds concerning, osteogenic and angiogenic responses are addressed. In this study The current knowledge on the bone tissue engineering scaffold and their clinical implication has been discussed. Inductive couple plasma mass spectroscopy was carried out to determine the release of zinc, strontium, phosphorous and cobalt within bioactive glass and bone scaffolds over period of time. ICP Vista Pro was used to carry out inductive couple plasma mass spectroscopy. The results show significant amount of release of cobalt,, zinc and strontium over period of time which confirmed the bioactive nature of glasses and justified the properties of ions released by glasses and scaffolds. The diversity of the bioactive glasses and bioactive scaffolds and their complex nature leaves enough space for the studies to be carried on.

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