Muhammad Afzal, Shahida Husain Tarar, Syed Muhammad Ali Shah.
Spectrum of Endoscopic findings in patients with Liver Cirrhosis due to Chronic Viral Hepatitis.
Pak J Med Health Sci Jan ;12(1):10-3.

Background: Liver cirrhosis is a clinico-pathologic condition that is characterized by hepatic fibrosis, nodular regeneration, and distortion of hepatic architecture. Esophageal varices and portal hypertensive gastropathy are most common lesions found in patients with liver cirrhosis but there is variety of endoscopic findings found in patients with liver cirrhosis so the aim of study is to determine frequencies of different types of upper gastrointestinal lesions on endoscopy. Aim : To determine frequencies of different types of upper gastrointestinal lesions on endoscopy in patients with liver cirrhosis presenting at Aziz Bhatti Shaheed Teaching Hospital Gujrat. Methods : Observational cross sectional study was conducted at Aziz Bhatti Shaheed Teaching Hospital Gujrat from January 2015 to January 2017. 830 patients aged more than 18 years who presented liver cirrhosis due to chronic viral hepatitis were included. Frequency of different lesions like esophageal varices, fundal varices, portal hypertensive gastropathy, peptic ulcer disease and acute erosive disease were noted. Data analysis was done using SPSS 20.0. Results : Out of 830 patients 413 (49.8%) were male and 417 (50.2%) were female with mean age of 52.62 +/-10.98 years. 579 (69.76%) were chronically infected with hepatitis C, 158(19.03%) with chronic hepatitis B and 93 (11.21%) were co-infected with both HBV and HCV. Most common finding was esophageal varices (90.48%) followed by poartal hypertensive gastropathy (70.2%), acute erosive disease (16.39%), gastric varices (6.3%), peptic ulcer disease (2.3%), hiatus hernia (1.8%) and esophageal candidiasis (1%). Conclusion : A vast spectrum of endoscopic findings is observed in patients with liver cirrhosis esophageal varices being most common finding.

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