Muhammad Asif, Imtiaz Ahmad, Il Khan W Asil, Sania Khattak.
Comparison of Serum Leptin Level in Preeclamptic and Normotensive Pregnant Women.
Pak J Med Health Sci Jan ;12(1):117-8.

Aim : To compare the serum leptin levels in normotensive pre- eclamptic pregnant women and to investigate the possibility of leptin being a marker of severity of pre-eclampsia. Study Design: Comparative cross-sectional Place of Study: Pathology , Gynaecology/obs and medicine department Saidu teaching hospital Swat. Methodology: This was a comparative cross-sectional study 45 primigravidas with normal and 45 primigravidas with pre-eclamptic pregnancy were chosen in third trimester. Serum leptin levels were determined by immunoenzymometric assay. Results: Blood leptin levels were elevated in pre-eclamptics as compared to normal pregnancy. Serum leptin were increased in severe group of preeclamptics . Conclusion: Blood leptin were raised in pre-eclamptic group in third trimester and used as a marker of pre-eclamptic condition.

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