Zareena Yaqoob, Muhammad Tahir, Muhammad Haroon.
Outcome of Pancreatic Necrosectomy for Infected Pancreatic Necrosis in Terms of perioperative Mortality.
Pak J Med Health Sci Jan ;12(1):315-8.

Aim: To determine the outcome of pancreatic necrosectomy for infected pancreatic necrosis in terms of perioperative mortality at Shaikh Zayed Postgraduate Medical Institute. Methods: This descriptive case series study was carried out in the Department of General Surgery at Shaikh Zayed Postgraduate Medical Institute, Lahore for six months. The Non-probability consecutive sampling technique was used to include patients. Informed consent was taken from all the patients. Basic information of all patients was recorded. The subject patients went through a clinical assessment to determine history of their previous illness. The level of their illness i.e. severity was examined using Ranson’s score ≥ 3. Closed continuous lavage of the lesser sac and retroperitonium technique was used to operate all patients. Dead tissue was removed and necrotic tissue was unbridled, material of pus was cleared, surgical procedures like cholecystectomy and jejunostomy were carried out for enteral feeding in all cases. To clear debris and presence of amylase, drain system was used to close abdomen and continuous efflux was performed after operation until it was noted that effluent has become clear of above mentioned substances. Due to the sensitivity factor of necrotic tissue, antibiotic therapy was initiated after operation. Surgical records were obtained and subject patients were monitored for over 30 days after their surgery. All the gathered data was catalogued on a precisely designed research Performa. SPSS version 16 was used to analyze all the sample data. Results: In this study total 50 cases were enrolled, the mean age of the patients was 44.18±8.57 years and the male to female ratio of the patients was 2.5:1. The mortality occurred in 13(26%) patients. sepsis was found in 6(12%) cases, multiple organ failure was noted in 4(8%) cases and hemorrhage was found in 3(6%) cases. Conclusion: According to our study the mortality occurred in 26% patients after open surgery of infected pancreatic necrosis.

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