Faiza Irum, Shazia Anwar, Muhammad Junaid Mushtaq.
Frequency of Raised Serum CRP in acute pancreatitis - a Cross- Sectional study at Lahore General Hospital.
Pak J Med Health Sci Jan ;12(3):999-1001.

Aim: To determine the frequency of raised CRP levels amongst patients with acute pancreatitis. Study Design: In this descriptive cross-sectional study. Place and Duration: From January 2017 to December 2017, medical unit 01, Lahore General Hospital, Lahore. Methods: 100 acute pancreatitis patients were enrolled. Patients of either gend er aged between 15-70 years presenting with acute severe epigastric pain radiating to back and diagnosed as acute pancreatitis by serum amylase of 1000 units or more were included in the study. Those with history of any severe comorbid illness e.g ., renal failure, chronic liver disease etc and any chronic inflammatory disorder were excluded from the study. Detailed clinical history was taken in each case to find out the cause of acute pancreatitis. Ranson Score and C reactive protein levels on admission were noted. A ranson score of 0-2 was considered mild; 3-5 as moderate and >6 as severe pancreatitis. A CRP level of >10mg/l was considered as raised. All the data was recorded on a pre- designed proforma and analyzed by SPSS version 21.0. p-value < 0.05 was taken as statistically significant. Results: Out of total 100 cases, raised CRP levels were observed in 92 (92%) patients. Mean CRP level was found to be 34.23+/-10.78mg/dL. All the patients with moderate and severe disease were found to have raised CRP levels. Upto 89.2% (66) of the mild cases also had raised CRP levels. Conclusion: CRP levels offer a simple yet non invasive screening tool for detecting the presence of acute pancreatitis.

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