Hanzla Khalid, Fouad Nafees, Muhammad Adnan Khaliq.
Infective Organisms and their Changing Antibiotic Sensitivity Trends in Surgical Site Infection after Orthopedic Implant Surgeries.
Pak J Med Health Sci Jan ;12(3):1256-8.

Background: In orthopedic surgeries, surgical site infection (SSI) has been reduced in recent decades with the help of several antibiotics and development of surgical techniques. But still SSI is a common finding of orthopedic surgery. There is lack of evidence regarding most common pathogen and its sensitivity pattern after orthopedic surgery. Aim : To assess the frequency of Infective organisms and their changing antibiotic sensitivity trends in surgical site infection after orthopedic implant surgeries Methods: 140 consecutive patients with surgical site infection after elective surgeries were included in the study from June to December 2017. Patients demographics were recorded. Type of most common pathogen and its sensitivity pattern were recorded. Data was a recorded on proforma and analyzed through SPSS v. 21.0. Results: The mean age of patients was 45.93 +/- 10.58 years. There were 51(53.1%) males and 45 (46.9%) females. Out of 140, Staph Aureus was found in 23 (23.96%) cases, MRSA was found in 18 (18.75%) cases, E. Coli was found in 15 (15.63%) cases. Ceftriaxone was sensitive in 88 (91.7%) cultures, Ampicillin was sensitive in 62 (64.6%) cultures, Metronidazole was sensitive in 58 (61.4%) cultures. Conclusion: The frequency of Staph aureus was found to be most common pathogen in SSI and ceftriaxone was most sensitive antibiotic for SSI management.

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