Rehan Anwar, Syed Shaheer Haider, Shazia Anwar.
Association between High sensitivity CRP and Ischaemic stroke - a case control study.
Pak J Med Health Sci Jan ;12(4):1773-6.

Background: Stroke also referred to as cerebrovascular accident (CVA) occurs when reduced blood flow to the brain results in cell death. Aim: To determine the association between high sensitivity C-reactive protein and ischemic stroke patients. Study design: Case-control study Settings Department of Medicine, Allama Iqbal Memorial Teaching Hospital Sialkot . Duration: 06 months i.e. 1st January, 2018 to 30 th June, 2018 Methods : Ischemic stroke presenting to outdoor, indoor and emergency department of Allama Iqbal Memorial Teaching Hospital Sialkot was offered to be enrolled in the study. Blood samples were withdrawn from cases at the time of presentation in emergency for baseline laboratory examination. Serum Hs CRP levels was measured. Data was collected in a predesigned proforma containing background information like age, sex and Hs CRP level along with history of current smoking and presence of dyslipidemia to allow for effect modification. Results : Mean age (years) in the study was 58.53 +/-13.01 whereas mean serum high sensitivity CRP was 4.67 +/-2.92. There were 33(33 %) male and 67(67 %) female patients who were included in the study whereas raised hs CRP among both the groups was 30(60 %) and 4(8 %) respectively which showed that there is an association between high sensitivity C-reactive protein and ischemic stroke patients was statistically significant (p- value 0.000). Conclusion : There is an association between high sensitivity C- reactive protein and ischemic stroke.

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