Ayesha Ilyas, Saima Iqbal.
Comparison of Mean Pain Score with Vitamin E in Combination with Mefenamic Acid Versus Mefenamic Acid Alone for Management of Primary Dysmenorrhea.
Pak J Med Health Sci Jan ;13(1):96-8.

Background: Primary dysmenorrhea is a usual and most common gynecological complaint, mainly in teenagers, that is described as a cramping pain in the lower abdomen during menstruation in the absence of any pelvic pathology. Aim: To compare the mean pain score with vitamin E supplementation in combination with mefenamic acid versus mefenamic acid alone for the management of primary dysmenorrhea. Methods: This randomized control trial was conducted in Gynae Unit II, Services Hospital, Lahore. It was done for six months from July to December 2016. The technique used was non-probability, consecutive sampling technique conducted after taking Informed consent from all the patients. The data was collected in the forms of two groups. Data analysis was done on SPSS version 16. Results: In our study the mean age of the female patients was 14.96+/-2.05 years. The mean value of BMI of the group A patients was 20.51+/-1.34 kg/m2 and its mean value in group B patients was 20.58+/-1.35 kg/m2. Statistically highly significant difference was found between the study groups with the pain score of the patients i.e., pvalue=0.000. Conclusion: The combination of Mefenamic acid with vitamin E is significantly more effective and showed reduced pain score compared to Mefenamic acid alone for management of primary dysmenorrhea.

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