Anwar Ali, Mohammad Hanif, Sohail Waheed.
To study the effects of Citalopram and Escitalopram on blood levels of FSH and Testosterone in Female Albino Rats.
Pak J Med Health Sci Jan ;13(1):107-8.

Aim: To compare the effects of different doses of citalopram and Escitalopram i.e. 10mg and 40 mg on blood levels of testosterone and FSH female albino rats. Methodology: Fifty female albino rats were selected and were divided into five groups. Group A was control group and B, C, D, E were with different doses of medicines. Rats were given 10mg and 40 mg of citalopram and Escitalopram. Group A (Control group) with distilled water orally. Total duration was 28 days. Quantitative assay of FSH and testosterone were performed by ELISA method. Results: When comparing with controls, non significant changes were observed in low and high dose groups. So the Citalopram and Escitalopram have little effect on testosterone and follicle stimulating hormone. Conclusion: Citalopram and Escitalopram have non-significant effect on serum testosterone and follicle stimulating hormones.

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