Safdar Hussain Arain, Hamid Akbar Shaikh, Najm-us Saqib.
Analyze the Outcomes of Decompressive Craniectomy with Malignant Ischemic Infarct (Middle Cerebral Infarcts).
Pak J Med Health Sci Jan ;13(1):317-9.

Aim: To examine the functional outcome of decompressive craniotomy treatment in patients diagnosis with malignant cerebral artery infarction. Study Design: Retrospective cohort study. Place and Duration of Study: Department of Neurosurgery, Per Syed Abdul Qadir Shah Jillani Institute of Medical Sciences, Gambat from 1 st June 2017 to 31st December 2017. Methods: A Total 29 patients of both genders diagnosis with middle cerebral artery infarction were included in this study. Patient’s ages were ranging from 35 to 70 years. Patient’s detailed medical history was examined after taking written consent. Patients with previous history of craniectomy, preexisting significant disability mRS > 4, patients with pregnancy and life expectancy <3years were excluded from study. Mortality rate and functional outcome was recorded after decompressive craniectomy at 1, 3 and 6 months. Modified Rankin Scale<3 and mBI > 60 considered as a favourable outcome. Results: Out of 29 patients, 19 (65.52%) patients were males and 10 (34.48%) patients were females.7 (24.14%) patients had ages of 35 to 45 years, 12 (41.38%) patients were ages between 46 to 55 years and 10 (34.48%) patients had ages 56 to 70 years.17 (58.62%) patients had right hemisphere infarction while 41.38% had left. Overall mortality rate was 17.24% at six months after surgery. 13 (54.17%) patients had favorable outcomes on mRS and on mBI it was 50%. There was no major difference found according to outcomes p-value 0.072. Conclusion:It is concluded that decompressive craniectomy declare better results regarding deaths in patients with middle cerebral infarct, but regarding functional outcomes at six months it shows poor results.

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