Zulfiqar Ali, Muhammad Naim, Danish Gani, Muhammad Siddique, Faisal Rashid, Sajjad Muhammad Haider.
Comparison Between the Efficacy of Intracameral Injection Dexamethasone and Subconjunctival Injection Dexamethasone in Preventing Post-Operative Inflammation After Phacoemulsification.
Al-Shifa J Ophthalmol Jul ;14(4):176-82.

Objective: To compare the efficacy of Intracameral injection of dexamethasone and subconjunctival injection of dexamethasone in preventing post-operative inflammation after phacoemulsification. Study Design: Randomized controlled trial. Place and duration of study: Department of Ophthalmology, Sheikh Zayed Medical College and Hospital, Rahim Yar Khan from 16th January 2016 to 15th July 2016. Subjects and Methods: A total of 74 patients, 50-70 years of age with senile cataract were included in this study. Patients with anterior uveitis, any ocular pathology, previous ocular surgery and co-morbid conditions were excluded. Then selected patients were randomly assigned into two groups i.e. Group-A (subconjuctival dexamethasone) and Group-B (intracameral dexamethasone). Outcome variables like efficacy i.e prevention of post-operative inflammation, were noted. Results: The mean age of patients in group-A was 62.71 +- 4.97 years and in group-B was 62.52 +- 5.06 years. Out of 74 patients, 49 (66.22%) were males and 25 (33.78%) were females with male to female ratio of 1.96:1. Efficacy of subconjuctival dexamethasone group was 16 (43.24%) while intracameral dexamethasone group was 26 (70.27%) with p-value of 0.019 which is statistically significant. Conclusion: This study concluded that Intracameral injection of dexamethasone is better and more efficacious than subconjuctival injection of dexamethasone in preventing post-operative inflammation after phacoemulsification.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com