Masroor Ahmed, Ghulam Hussain, Mukesh Kumar, Rukhsana Hamid, Nida.
Reduction in blood loss with tranexamic acid in dynamic hip screw surgery for intertrochanteric hip fractures.
Rawal Med J Jan ;44(1):79-82.

Objective: To evaluate the efficacy of tranexamic acid in reducing blood loss in patient undergoing dynamic hip screw (DHS) surgery for intertrochanteric fracture. Methodology: In this randomized control trial, 120 patients undergoing DHS surgery between July 2015 to July 2017 were randomly divided into two groups (60 cases in each group); group A (intervention group: received 15mg/kg tranexamic acid), whereas group B (control group: given same dose of physiological saline). The age, weight, duration of fracture, height, pre-op and post-op hemoglobin and HCT and estimated blood loss were recorded and compared in two groups. Results: Preoperative and post hematocrit values were significantly different in two groups (p value 0.01 and 0.001, respectively). The mean estimated blood loss was 395.78+-204 in group A and 427.8+-146.9 in group B (p=0.001). Conclusion: Treatment with Tranexamic acid had decreased the blood loss during intertrochanteric hip fracture surgery.

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