Sabeen Adil, Faiqa Aslam, Muhammad Usman.
The frequency of infectious complications between mechanical bowel preparation and no preparation in elective colonic surgery..
Professional Med J Jan ;27(03):594-600.

Mechanical bowel preparation (MBP) is the cleansing technique used clean up the large gut using oral cathartic agents like polyethylene glycol, sodium phosphate, sodium Pico sulfate, and magnesium citrate. Objectives: To compare the frequency of infectious complications between mechanical bowel preparation and no preparation in elective colonic surgery. Study Design: Randomized control trial. Setting: OPD or Indoor Surgical unit 5, DHQ Hospital, Faisalabad. Period: 1st January 2017 to 31st Dec 2018. Material & Methods: Patients diagnosed of malignant tumors of colon, appendix or cecum were included in study. Group A: mechanical bowel preparation done according to standard protocols, group B no mechanical bowel preparation was done. All patients were followed regularly for 2 weeks for presence or absence of surgical site infections and anastomotic leakage. Results: In this study, surgical site infection in both groups was compared, it shows that 18.59% (n=37) in Experimental group and 9.55% (n=19) in Control group had SSI while 81.41% (n=162) in Experimental group and 90.45% (n=180) in Control group bad no SSI, p - value was calculated as 0.009 showing a significant difference. Comparison of surgical anastomotic leakage in both groups was done, it shows that 2.51% (n=5) in Experimental group and 1.51% (n=3) in Control group had anastomotic leakage, p - value was calculated as 0.47 showing insignificant difference. Conclusion: We concluded that no mechanical bowel preparation is significantly better than mechanical bowel preparation in elective colonic surgery in terms of post-operative surgical site infection.

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