Iram Jehan Balouch, Abdul Karim Soomro, Sobhya Bhutto, Sarwat Anjum, Muhammad Akbar, Shoukat Ali Memon.
Serum Uric Acid in Systemic Hypertension patients and its association with Systolic and Diastolic Blood Pressure.
Med Forum Jan ;31(1):75-8.

Objective: Evaluating the Serum Uric acid (SUA) in Systemic Hypertension Patients and its association with Systolic (SBP) and Diastolic Blood Pressure (DBP). Study Design: Cross sectional study Place and Duration of Study: Department of Medicine, Isra University Hospital from April 2017 - February 2018. Materials and Methods: A sample of 100 diagnosed cases of essential systemic hypertension and 100 controls were selected according to the inclusion and exclusion criteria. Venepuncture was done to collect 2 ml venous blood. The blood samples were centrifuged. Sera were used for the uric acid estimation. Volunteers were asked to give consent in written. A pre- structure performa was used for data collection. Data was analyzed on statistical software (SPSS v 22.0, IBM, Incorporation, USA) at confidence interval of 95% (P <= 0.05). Results: Mean +- SD age was found 50.32+-4.13 and 50.25+-4.20 years in control and cases respectively (p=0.95). Male population was predominant in present study. Serum uric acid in control and cases was found as 4.42+-1.10 and 5.28+-1.04 respectively (P=0.0001). Pearson`s correlation shows positive association of Serum Uric acid with systolic BP (r= 0.575**, p=0.0001), Diastolic BP (r= 0.561**, p=0.0001) and Body weight (r= 0.132, p=0.063). Conclusion: The present study reports raised serum uric acid levels in systemic hypertension. Serum Uric acid shows a definite positive correlation with systolic and diastolic blood pressure

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