Khuram Shazad, Rashid Mahmood, Abdullah Mashori, Syeda Asya Parveen, Farooq Muanfat.
Cardiac Enzymes in Acute Coronary Syndrome.
Med Forum Jan ;31(1):38-42.

Objective: The present study was conducted on specific population of Mirpur Azad Kashmir to observe the behavior of the MI evaluating various cardiac biomarkers for the detection of ACS in relation to age, gender and risk factors. Study Design: Case control study Place and Duration of Study: This study was conducted at the Indoor Patient Department Kashmir Institute of Cardiology Mirpur, Azad Jammu and Kashmir from June 2013 to July 2014. Materials and Methods: Total 240 patients were recruited in the study. 120 admitted patients of Acute Myocardial Infarction (AMI) in Kashmir Institute of Cardiology were registered as cases. 120 age and sex matched controls were included in the study. Informed written consent was obtained by the participants of study. Detailed medical/surgical history was obtained and recorded. Results: The cardiac enzymes used as biomarkers of myocardial infarction (MI) have been assayed in MI affected and compatible non MI control subjects. The pertinent cardiac enzymes in related to MI included CK-NAC and LDH. The responses of the cardiac enzymes have been analyzed in relation to age. Conclusion: It is concluded in this study that, in all the subjects of study, main cardiac enzymes CKNAC and LDH concentrations were increased in MI patients as compared non-MI subjects. This study also concludes this significant rise of CKNAC in younger group and that of LDH in oldest age group.

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