Umbrin Naz, Fazal Wadood, Aurangzeb Aurangzeb, Muhammad Ilyas, Ambareen Sifatullah, Rubina Bangash.
Effectiveness of low dose ketamine and lignocaine in prevention of propofol induced pain.
J Med Sci Jun ;28(1):16-20.

Objective: To prove that low dose ketamine is more effective than lignocaine in prevention of propofol injection pain.Materials and Methods: This randomized controlled trial study was conducted in the central operation theatre of Khyber Teaching Hospital ,Peshawar-Pakistan, from July 2018 to December 2018. A total of 174 patients were randomly allocated in two groups by lottery method. Patients in group A (n=87) received Ketamine 0.5 mg/kg and patients in group B (n=87) received 0.5 mg/kg of 2% Lignocaine for prevention of propofol induced pain. Pain scores were calculated through visual analogue scale (VAS).Results: The mean VAS score in group A was 2.264+-0.990 and in group B was 4.540+-1.070. There was statistical difference between the two groups (p<0.05).Conclusion: Ketamine is more efficacious than lignocaine in reducing injection site pain caused by propofol.

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