Syed Shafique Rehman Shah, Pir Bux Ghumro, Bashair Ahmed Shaikh, Aftab Hussain Shah, Imdad Ali Ansari, Marvi Gurbakhshani.
Helicobacter pylori: determine the frequency of infection in patient of acid peptic disorders.
Pak J Med Health Sci Jan ;13(4):753-5.

Aim : To determine the rate of H. pylori infection in patients presented with acid peptic disorders. Also examine the association of serology test (immune chromatographic test) with histopathological examination. Study Design: Prospective / Observational study. Place and duration of study: Department of Medicine, Chandka Medical Collage Hospital Larkana from 1st January 2019 to 30 th June 2019. Methods : Total 154 patients of both genders with ages 20 to 65 years presented with acid peptic disorders were included. Patients detailed demographic were recorded after written consent. Two biopsies of each individual were performed for histopathology examination and blood samples were taken for immune-chromatographic procedure for antibodies for H. pylori. Association between ICT antibodies and histopathology examination were examined. Results: Out of 154 patients 82 (53.25%) patients were males while 72 (46.75%) were females with mean age 42.26 +/- 9.54 years. Upper abdominal pain was the most common symptom found in 108(70.13%) patients. H. pylori infection was positive in 124 (80.52%) patients by histopathology examination and 118 (76.62 %) patients had H. pylori positive by ICT antibodies examination. Conclusion: The rate of H. pylori infection in this area is quite high. It may be due to unawareness and poor sanitation. Immunechromatographic for antibodies examination for H. pylori is safe and accurate procedure after histopathology examination.

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