Fareeha Khan, Shahnila Zafar, Sadaf Khurshid, Sadia Mustafa.
Association of adverse perinatal outcome with oligohydramnios in pregnant females.
Pak J Med Health Sci Jan ;13(4):962-5.

Background: Amniotic fluid serves as a cushion for growing fetus along with provision of a feasible environment for growth. Oligohydramnios is a common complication which is frequently encountered in pregnant patients. It may have sever implications and may have a poor outcome of pregnancy. Aim : To determine the association of adverse perinatal outcome with oligohydramnios in pregnant females. Methods : This case-control study was conducted at Department of Obstetrics & Gynecology, Fatima Memorial Hospital Lahore . The duration of this study was one year from January, 2018 to December, 2018. A total of 242 females were enrolled. Two groups of participants were made i.e. , group I with oligohydramnios (Cases) having low Amniotic Fluid Index (AFI) and group II with normal AFI (Controls) . Patients were followed up till delivery of the fetus and then perinatal outcome was noted. All the collected data was entered and analyzed on SPSS version 20. Results : A total of 242 females were enrolled. The clinical and demographic variables of patients including age, parity, gestational age and BMI were comparable in both groups. The CS rate was significantly higher among cases than controls (RR = 0.693). Poor Apgar score (RR=0.615 [0.436 -0.867]) and low birth weight were also significantly higher among Cases than Controls (RR=0.631). All parameters of outcome were stratified by age, gestational age, parity and BMI and outcome was poor among Cases than controls. . Conclusion : Adverse perinatal outcome including CS, poor Apgar score and LBW were associated with increased risk with oligohydramnios in pregnant females.

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