Muhammad Latif Aftab, Muhammad Nasir, Noor-ul Hassan, Umar Farooq.
Role of neutrophil to lymphocyte ratio in diagnosis of cholecystitis.
Pak J Med Health Sci Jan ;13(4):989-91.

Aim : To determine diagnostic accuracy of preoperative predictivity of neutrophil to lymphocyte ratio in patients with acute cholecystitis taking histopathology as a gold standard. Methods: This was a multi-centric study conducted at different tertiary care hospitals of Lahore. A retrograde record of CBC and Histopathology reports was taken of 52 cases of cholecystectomies. The report of NLR ( ≥ 3) was compared with their final diagnosis on histopathology . All the data was entered and analyzed on SPSS version 23 to find out mean and standard deviation of age. The Sensitivity, Specificity, PPV, NPV and Diagnostic Accuracy was calculated to assess the diagnostic role of NL Ratio in diagnosing cholecystitis. Results: In our study the average age of the patients was 52 years, the male to female ratio was 1: 1.41 . The sensitivity, specificity, PPV, NPV and diagnostic accuracy of NLR was 79.31%, 78.26%, 82.14%, 75% and 78.84%. Conclusion: According to our results the preoperative neutrophil to lymphocyte ratio (NLR ) ≥ 3 is useful and reliable predictor of severe cholecystitis in patients with acute cholecystitis.

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