Ahsan Jamil, Haseeb Khan, Jahanzab Salim, Ijaz Amin, Sabahat Zulfiqar, Talha Laique.
Effect of basal metabolic rate on blood loss and hospital stay during thyroidectomy among Pakistani patients with harmonic scalpel.
Pak J Med Health Sci Jan ;13(4):1168-71.

In general surgery thyroidectomy is the most common operative procedure. Blood loss with hospital stay of patients after surgery depends on the method adopted during it. In conventional method, silk sutures are employed. Aim : To compare the effect of BMI on blood loss and hospital stay of Pakistani patients with multi -nodular goiter undergoing thyroidectomy with harmonic scalpel versus Conventional suture method. Study design : It was prospective randomized controlled trial . Methodology: All patients (60) underwent thyroidectomy for multinodular goiter were distributed into two assemblies, In Group A, harmonic scalpel ligated all thyroid vessels. In Group B, inferior middle and superior were tied using silk sutures 3/0, and all other vessels were sutured by 4/0 or electrocauterized. The two groups were compared for post-operative hospital stay and intra-operative bleeding during procedure. Results: The mean blood loss and hospital stay of patients in group A was 70.03±5.70ml and 2.9±0.8 days whereas in group B was 96.43±5.93 ml and 4.2±0.7days with p-values of 0.00001 and 0 .00002 respectively. Statistical analysis : All the data was entered and processed by analysis made using SPSS v23.0. Conclusion : Harmonic scalpel can be employed regularly as a safe procedure with good hemostatic control and short duration of hospital stay for thyroidectomy patients.

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