Sharjeel Sultan, Sheed Khokar A Rasheed, Nazish Waris, Nisar A Siyal.
Assessment of anterior chamber angles for detecting eyes with narrow angles: an anterior segment OCT Study.
Pak J Surg Jan ;35(2):156-61.

Objective: The detection of eyes with narrow angles in respect to an anterior chamber angles with anterior segment optical coherence tomography. Study design: Retrospective observational study Sett ing and duration: This study was conducted at Civil hospital Karachi-Pakistan from September 2017 to October 2018. Material and Methods: Medical and ophthalmic history with shallow anterior chamber on slit-lamp evaluation were obtained. Anterior segment imaging by AS-OCT, anterior chamber depth, axial length (mm) measurements and intraocular pressure (IOP, mmHg) were noted. Refractive status was recorded as patients with hyper-matrop and myopia. Nasal and temporal angles were evaluated. The algorithm then automatically calculated following angle measurements: angle opening distance (AOD), angle recess area (ARA ), and trabecular-iris space area (TISA). Results: Total of 58 eyes of 32 patients were observed into this study. Of these, 23(39.7%)were males and 35(60.3%)were females. The mean +- SD age was 56.23+-7.4 years. The mean +- SD of IOP (mmHg) was 14.6+-2.5, axial length (mm) 22.32+-1.21 and central ACD (mm) 3.24+-0.43. The AUCs were highest for AOD750 (0.89) in nasal quadrant and (0.88) in temporal quadrants. Th e AUCs for ARA 750/ TISA750 in the nasal quadrants were 0.79/0.85 and temporal quadrants were 0.80/0.87. At 225 and 258 um cutoff values of AOD750, the highest AUCs of sensitivity and specificity were observed for both nasal quadrants and temporal quadrants. Conclusions: AS-OCT is more sensitive in identifying narrow angles with good repeatability and reproducibility. Either, it has low specificity, but, it has a significant impact as the new posterior segment imaging device.

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