Sohail Sabir, Halim S A.
Goodpasture`s Syndrome.
Pak Armed Forces Med J Jan ;53(1):92-5.

A 29-year-old male soldier was admitted with one-week history of low grade fever and cough with expectoration of blood stained sputum. One week prior to admission, he started coughing out blood stained sputum with occasional episodes of hemoptysis. He had low-grade fever and generalized aches and pains. There was no hist of rash, bleeding from any other site, urinary bowel complaints or weight loss. His physic examination was unremarkable except for few crepitations at the right upper chest. His urine examination reveal numerous RBC`s, blood ESR was 55mm, Hb 12.4g/dl, TLC 6100/mm3 Sputum for AFB was negative for consecutive days. Mantoux test was negative. Chest x-ray PA view revealed pneumonitis on right side. Haemoptysis persisted and a day later he developed peripheral oedema. Ultrasound showed bilaterally enlarged kidneys without hydronephrosis. Renal biopsy revealed crescentic glomerculonephritis with immunofluorescence showing linear staining of IgG on basement membrane of all glomeruli. The final diagnosis of Goodpasture`s syndrome was made, and was confirmed by detection of anti-GBM antibodies.

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