Shiraz Shaikh, Shahida Khatoon, Zameer Hussain Laghari, Qamber Ali Laghari, Shahnawaz Abro.
Comparison of Outcome of one Versus two Drains Insertion for Seroma Formation Following Modified Radical Mastectomy in Breast Carcinoma.
Ann Pak Inst Med Sci Jan ;17(1):59-63.

Objective: Comparative outcome of one versus two drains insertion for in the term of seroma formation following modified radical mastectomy in breast carcinoma Methodology: This Prospective Interventional trial was conducted at department of General Surgery, Liaquat University Hospital Hyderabad form February 2018 to January 2019.  Females with breast carcinoma, admitted for modified radical mastectomy were included. Patients were divided into two groups I underwent one drain placement and group II underwent two drains placement. All patients were observed for measure and record the volume of the fluid. Patients were discharged from Hospital on stable condition and after removal of drains, and followed up weekly for the period of one month. Data was recorded on self-made proforma and analyzed by using SPSS-20. Results: Total 80 patients were selected, 38 in group A and 42 in group B. Mean age of patients of group A was 49.08 ± 9.89 years and group B was 51.40 ± 13.59 years. , Excised Mass weight was lesser in group A as compared to group B. Mean volume of drain discharge was significantly higher in Group B 323.43 ± 158.88 ml, while it was in group A 230.29± 200.98, findings were statistically significant 0.013. Seroma formation was statistically insignificant among both groups as 8(21.1%) in group a and   10(23.8%) in group B, p-value 0.768. Conclusion: One-drain and two-drain insertion are equally effective to reduce the seroma formation after modified radical mastectomy; however, one drain insertion leads to more patient compliance and comfort with probably less morbidity and cost.

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