Moin Uddin A S M, Chandana Sultana, Md A Muntakim Shahid, Mohammed Rashed, Mohammad Shamsal Islam.
Indications and outcomes of penetrating keratoplasty at a tertiary hospital in bangladesh.
Pak J Ophthalmol Jan ;36(4):22-3.

Purpose: To find out the indications and outcomes of Penetrating Keratoplasty at a tertiary eye hospital in Dhaka, Bangladesh. Study Design: This was a retrospective hospital based study. Place and Duration of Study: Ispahani Islamia Eye Institute and Hospital, Dhaka, Bangladesh from July 2011 and July 2018. Methods: In this study, data was collected from the records of patients, who came for treatment at the cornea unit. Pre-operative evaluation and post-operative follow-up record was analyzed. Patents demographic information, visual acuity, management, pre and post-operative complications, follow-up visits and outcomes were recorded. A technical research team headed by a senior consultant determined the content validity and their comments were incorporated in finalizing the research instruments. Results: A total of 213 penetrating keratoplasties (PK) were performed during the study period. The main indications were keratoconus (8.28%), Corneal scarring (41.42%), Adherent leukomas (25.59%), corneal dystrophy (3.84) and bullous keratopathy (7.25%). Rejection rates at 8 years were 5.62%. Keratoconus showed the best graft survival (79%). The percentage of patients with post-transplant best-corrected visual acuity of 6/36 at 8 years was 52%. There was a statistically significant reduced rejection rate in males. Conclusion: Penetrating Keratoplasty is an effective treatment option for improving visual outcomes for people with visual impairment. There are many co-factors involved with a quality outcome of patients with Penetrating Keratoplasty such as immunological rejection, microbial keratitis and patient level of awareness, which continue to limit the success.

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