Aftab Anwar, Shuja-ur Rehman, Amna Nazar, Saed Aftab Ahmad.
Spectrum of Microorganisms Causing Colonization of Central Venous Catheter in Pediatric ICU.
Pak Paed J Jan ;45(1):69-73.

Objective: To determine the spectrum of microorganisms causing colonization of central venous catheter in pediatric ICU. Study Design: Cross-sectional study. Place and Duration of Study: Department of Pediatric ICU, the Children`s Hospital & the Institute of Child Health, Lahore, from July 2018 to February 2020. Material and Methods: 203 male and female children from 1 month to 15 years of age with a central venous catheter (CVC) during admission at the PICU were included. Specimens were taken from tip of catheter and sent to laboratory in a sterile container to identify the presence of microorganisms. Results: Of the 203 pediatric patients included, 123 (60.6%) were male and 80 (39.4%) were female with mean age of 5.65�1.374 years. Male to female ratio was 1:1.5 and age range was from 2-11 years. Organisms were identified in 88 patients (43.3%).Out of 88 cases positive cases, 22 (25%) had gram positive, 60 (68.2%) had gram negative and 6 (6.8%) had fungi isolated after culture. Klebsiella (30.7%) was the most common organism followed by Acinetobacter (21.6%) and Coagulase negative Staphylococci (17%). Conclusion: The prevalence of microbial colonization of CVCs is significant, 43.3% in our PICU. Gram negative (68.2%) organisms are commonly isolated from CVCs, Klebsiella (30.7%) being the most prevalent.

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