Sana Jahangir, Akhwand Abdul Majeed Jawed, Saaria Saeed Khan.
Comparison between 0.2% brimonidine tartrate and 0.03% bimatoprost in controlling increase in intraocular pressure after neodymium:yttrium-aluminium-garnet laser posterior capsulotomy.
J Sharif Med Dent Coll Jan ;2(02):66-8.

Objective: To compare the effectiveness of 0.2% brimonidine tartrate and 0.03% bimatoprost in controlling post Neodymium:Yttrium aluminium-garnet (Nd:YAG) laser capsulotomy intraocular pressure spike when given in a prophylactic manner. Methodology: A total of 90 patients divided in two equal randomised groups receiving either 0.2% brimonidine tartrate or 0.03% bimatoprost one hour before Nd:YAG laser capsulotomy. Intraocular pressure was measured one hour before and then one and three hours after the laser procedure. A pressure rise of more than 5mmHg was considered significant. Results: Results showed that 43 (95.5%) patients in group A had effective IOP control where 30 (66.66%) patients in group B had effective IOP control at 3 hours post Nd:YAG laser capsulotomy. There was statistically significant difference between two groups in regards with control of IOP (p-value <0.003). Conclusion: This study showed that prophylactic topical 0.2% brimonidine tartrate one hour before Nd:YAG laser capsulotomy effectively controls immediate post Nd:YAG laser IOP spike at three hours. Keywords: Posterior capsular opacity. Intraocular pressure. Cataract. Nd:YAG laser.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com