Salma Haq, Maria Aslam, Zarghoona Jafar.
Lipid profile in polycystic ovarian syndrome.
J Sharif Med Dent Coll Jan ;3(02):67-71.

Objective: To compare serum lipid profile of the patients with polycystic ovarian syndrome (PCOS) with normal healthy controls. Methodology: It was a cross-sectional study conducted in the Department of Pathology, Sharif Medical City Hospital, Lahore. The study included 120 subjects between the age of 18-40 years. They were divided into two groups. Group 1 included 60 patients of PCOS and group II consisted of 60 healthy females of same BMI and age group. Newly diagnosed patients of PCOS based on Rotterdam criteria were included in this study by random sampling technique. Lipid profile was performed on all subjects. Results: Mean age of the study patients included in group I was 33+7 years and in control group II mean age was 31+ 9 years. A statistically significant difference was found when serum lipid profile of both groups was compared. Serum total cholesterol, triglyceride, LDL and VLDL were significantly raised in patients with PCOS while serum HDL was low in the patient group as compared to controls Conclusion: Total cholesterol, triglycerides, LDL and VLDL levels were high and HDL level was low in patients with PCOS. So, it was concluded that dyslipidemia is an accompanying feature in patients with PCOS. Keywords: Polycystic ovarian disease. Dyslipidemia. Insulin resistance. Lipid profile.

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