Shazia Nazar, Sitwat Zehra.
Relationship between Atrial fibrillation and plasma omentin-1 levels in patients with coronary artery disease.
Rawal Med J Jan ;45(4):762-5.

Objective: To correlate the plasma omentin-1 with the presence of atrial fibrillation in patients with coronary artery disease (CAD). Methodology: This cross-sectional study was performed at cardiac unit of Civil Hospital Karachi, Pakistan, from June 2016 to March 2017. A total of 195 patients of coronary artery disease, and 150 without atrial fibrillation (AF) were included in the study. Diagnosis of AF was made on the basis of electro-cardio-graph. Plasma omentin-1 levels were determined by enzyme linked immunosorbent assay. Data were analyzed by using SPSS version 16. Results: Out of the 195 patients of AF (37 with permanent, 63 with persistent and 76 with paroxysmal AF), it was found that CAD patients with AF had reduced plasma omentin-1 levels (59.2+-9.10 vs. 96.9+-11.7, p<0.01). In addition, subgroup with permanent AF was found with significantly lessened omentin-1 as compared to other subgroups (37.4+-8.10, 63.3+-10.0, and 76.9+-12.7, p<0.01). Both simple and multivariable regression analysis revealed momentous association of plasma omentin-1 with less chance of developing AF. Conclusion: The risk of AF increases with lower plasma omentin-1 concentrations in coronary artery disease patients.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com