Laiba Shakori, Adila Ashraf, Shazia Abid, Agha Syed Ali Haider Naqvi, Saira Niaz.
Association Between Bacterial Vaginosis and Premature Rupture of Membrane (PROM) in Pregnant Women Presenting in a Tertiary Care Hospital.
J Akhtar Saeed Med Coll Jan ;3(2):57-62.

Background: Premature rupture of the membranes (PROM) is a frequent pregnancy problem. One of the most frequent causes of vaginal discharge in women is bacterial vaginosis. It has been hypothesized that PROM risks and the prevalence of bacterial vaginosis in pregnancy, as well as its connection with PROM, vary across populations. The study aimed to find out the association between premature rupture of membrane (PROM) and bacterial vaginosis in pregnant women presenting in a tertiary care hospital. Material and Methods: This was a six-month case control study performed in the Department of Obstetrics and Gynecology, Sheikh Zayed Hospital, Lahore. Sample size was 200 females; 100 females in each case and control group. Females were assessed for presence of signs of Bacterial vaginosis (BV). SPSS version 20 was used to perform statistical analysis on the obtained data. Results: The mean age of females in this study was 27.40 +- 4.90 years with minimum and maximum age of 20 and 35 years respectively. In cases and controls the bacterial vaginosis was seen in 24(24%) and 5(5%) of the females respectively. Significant association was observed between bacterial vaginosis in study groups (p-value < 0.001). There were 6 times more chances of PROPM in presence of bacterial vaginosis. Conclusion: Through the findings of this study, we found significant association between bacterial vaginosis and premature rupture of membrane in pregnant women. Bacterial vaginosis is preventable and curable condition. Therefore by early intervention and proper management we can minimize the risk of PROM.

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