Tazeen Fatima Munim.
Management of Eclampsia by diazepam infusion and oral nifedipine.
J Surg Pak Jan ;7(1):10-3.

To assess the response of oral nifedipine and diazepam infusion in the management of eclampsia, a prospective study extending over a period of three years was carried out at Abbasi Shaheed Hospital, Karachi. One hundred and twenty one patients suffering from eclampsia during a three years period from January 1998 to December 2000 were included in this study. They were managed by diazepam infusion and oral nifedipine for the control of convulsion and blood pressure. A response of these two agents on convulsion, blood pressure, maternal and foetal outcome is analyzed. During the three years period there were 121 eclamptics whereas there were 4,936 deliveries giving an incidence of 1:40.79 or 24.51 per 1000 deliveries .The fits were controlled with diazepam infusion in 117 patients(96.7%) while blood pressure was controlled with oral nifedipine in all the patients. There was a neonatal mortality of 7.3 per 1000 and maternal mortality of 1.4 per 1000. None of these were related to the treatment.

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