Mazhar Iqbal, Khalid Rasheed, Mohammad Iqbal, Asadullah Khan.
Aetiology of solitary Thyroid nodule.
J Surg Pak Jan ;7(4):28-30.

A Study was conducted in Ward-3 Jinnah postgraduate Medical centre, Karachi from January 1997 to December 2001 (5 years) to find the aetiology of solitary thyroid nodule in our setup. One hundred and one patients with Solitary Thyroid Nodules both males and females above 12 years of age admitted in ward 3 after carrying out all the necessary investigations for Solitary Thyroid nodules in the surgical outpatients were included in study. Hemithyroidectomies were performed and histopathological examinations were done at the Basic Medical Sciences Institute of the Jinnah Postgraduate medical Centre. The final diagnosis was made on histopathology. Relative incidence of Carcinoma Thyroid was very high (36.63%). Other causes of Solitary Thyroid Nodules were Nodular goiter (25.74%). Follicular adenoma (19.92%), Thyroiditis (10.89%), Cyst (3.96%) Colloid Goiter (1.98%) and Hyperplasia (0.99%). Incidence of Carcinoma Thyroid especially follicular is very high (36.63%) in our set up, as compared to other studies. In our study, leading cause was Carcinoma Thyroid so surgery should be the treatment of choice for Solitary Thyroid nodules.

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