Sana Abbas, Amjad Akram, Beenish Abbas, Mohsin Fayyaz, Basit Mehmood, Umer Hayat.
Local anaesthetic systemic toxicity awareness among clinical practitioners.
Pak Armed Forces Med J Jan ;71(5):1642-46.

Objective: to assess comprehension of local anaesthetic systemic toxicity among clinical practitioners. Study Design: Cross-sectional study. Place and Duration of Study: Tertiary Care Institute, from Dec 2019 to Mar 2020. Methodology: Methodology constituted of a web-based questionnaire. A pilot study carried out at 15-20 participants for questionnaire validation and reviewed by independent experts for face validity, a final questionnaire comprised of 10 multiple-choice questions in addition to demographic profile. Results: A total of 950 participants participated in the study and data was extracted from their responses. Out of 738 (77.8%) participants declared that they are unaware of local anesthetic systemic toxicity complication, 26 (2.7%) encountered local anaesthetic systemic toxicity and 185 (19.5%) never experienced. Ninety (9.5%) were aware of the availability and utilization of 'Lipid Emulsion' therapy to treat ‘Local Anaesthetic Systemic Toxicity’ (LAST). Conclusion: Although clinicians have significant awareness level regarding local anesthetic toxicity but unfortunately compliance with management of this life-threatening complication is deficient.

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