Shahid Hussain Mirani, Dileep Kumar, Muhammad Tanvir Iqbal.
Comparative study of Quality of Anaesthesia and Post-operative Analgesia with 0.5% Lidocaine and Lidocaine + Neostigmine in Intravenous Regional Anaesthesia.
Pak J Med Health Sci Jan ;14(2):592-4.

Aim: To compare the duration of anesthesia and analgesia in patients undergoing surgical procedures under intravenous regional anesthesia. Methods: This Randomized controlled trial was carried out in 2016 at Department of Surgery, GMMMC Sukkur. A total of 100 patients were included and they were divided in two groups, each group comprised 50 patients. Results: The onset of anaesthesia and quality of anaesthesia were better in neostigmine group (P<0.05). Post operative pain relief was also better. No significant difference in hemodynamics and no adverse effects were observed. Conclusion: With the addition of neostigmine in traditional lidocaine solution for intravenous regional anaesthesia (IVRA) the quality of anaesthesia and analgesia is improved.

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