Muhammad Azhar Ahmed, Syed Tabish Rehman, Gull Afshan Razi Zaidi, Nadeem Ahmed Rizvi.
Determine the Association between Chronic obstructive pulmonary disease and Osteoporosis in patients Visiting to a Tertiary Care Hospital.
Pak J Med Health Sci Jan ;14(2):584-7.

Aim: To determine the association between COPD and osteoporosis in patients visiting to a tertiary care hospital. Study design: Observational Case Control Study. Place and duration: Chest Ward, Jinnah Postgraduate Medical Centre, Karachi from 1st Jan 2018 to 31st Jan 2019. Methods: Thirty five male patients of chronic obstructive pulmonary disease was collected through registered out patients who visit for the routine check-up of COPD and fulfill the inclusion criteria were included in the study as cases and their relatives or attendant with no history of COPD and FEVI/FVC >= 0.7 were included as control. Mineral Density will be measured in cases and control by dual energy X-ray absorptiometry commonly known as Dexa Scan. Two x-ray beams with differing energy levels are aimed at the patient`s bones. Results: Mean age in cases and control were 61.57 +- 6.69 and 53.97 +- 7.08 years respectively. Mean FEVI in cases and control were 1.37 +- .49 and 2.17 +- 0.45 respectively. In comparison of cases and control significant association were found between COPD and osteoporosis i.e. (P=.004) and odd ratio (7.11) with C.I (1.82-27.79). Conclusion: There is a significant association between COPD and osteoporosis. Prevalence and severity of osteoporosis increased with the increase of COPD degree.

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