Zwan Hafeez M Rizwan, Sibgha Bashir, Jalil Iqbal, Adeel Zafar, Faghia Shahid, Rabia Saeed.
Examine the Prevalence of H. Pylori Infection Also Determine the Accuracy of Rapid Urease Test and Histopathology Examination for Diagnosing H. Pylori Infection.
Pak J Med Health Sci Jan ;14(2):569-71.

Aim: To examine the accuracy of RUT and compare with histopathology examination to diagnose H. pylori infection in patients presented with gastritis Study design: Prospective/Observational study Place & duration: Department of Pathology Shahida Islam Medical College Lodhran from 1 st March 2016 to 31st January 2017 Methods: A total 120 patients of both genders with ages 20 to 70 years having gastritis were included in this study. Four biopsies were taken from all the patients 2 biopsies were taken for the RUT and 2 for the histopathology examination. Sensitivity, specificity, PPV and NPV were examined of both methods. Results: Out of 120 patients 57 (47.5%) patients were males while 52.5% patients were females. 80 (66.67%) patients had H.pylori infection by Rapid urease test and 79 (65.83%) patients had H pylori infection as per histopathology examination. Association between RUT and Histopathology examination were noted as sensitivity, specificity, PPV and NPV as 96.20%, 92.5%, 95% and 90.24% respectively. Conclusion: It is concluded from this study that rapid urease test shows accurate results with no procedural complications. It is a good alternative to histopathology examination in patients presented with gastritis.

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