Kashif Zafar, Imran Abid, Zohaib Sadiq, Asim Iqbal, Nida Tasneem, Sohail Yousuf.
Severe Mitral Regurgitation after Inferior Wall Myocardial Infarction and Coronary Artery Dominance.
J Sharif Med Dent Coll Jan ;7(02):85-9.

Objective: To analyze the frequency of development of severe mitral regurgitation in patients with right or left coronary artery dominance after inferior wall myocardial infarction. Methodology: This cross-sectional study was conducted at the Emergency Department, Punjab Institute of Cardiology, Lahore for a period of six months. Two hundred and thirty patients presenting with inferior wall myocardial infarction (IWMI) were enrolled in the study by non-probability consecutive sampling. After informed consent and emergency treatment, echocardiography, and angiography of the patients were performed. Coronary artery dominance and the presence of severe mitral regurgitation (MR) were noted. The data was entered and analyzed in Statistical Package for the Social Sciences (SPSS) version 23.0. Results: The mean age of the patients was 52+/-13.73 years. There were 120(52.2%) males and 110(47.8%) females. The right coronary artery (RCA) was involved in 136(59.13%) while the left circumflex artery (LCX) was involved in 94(40.87%) of the IWMI patients. In patients having RCA as a dominant artery, severe MR was observed in 30(22.1%) while in patients having LCX as a dominant artery, severe MR was observed in 5(5.3%) cases. Out of 230 patients, heart failure was found in 107(46.5%) patients, hypertension in 114(49.6%), uncontrolled diabetes in 101(43.9%), and current smoking was found in 61(26.5%) patients Conclusion: Right coronary artery was the more common artery involved in IWMI. Patients with dominant RCA were more severely affected by MR as compared to the patients with LCX as dominant artery. Keywords: Mitral regurgitation. Coronary artery. Inferior wall myocardial infarction.

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