Ayesha Arif, Ayesha Sabir.
Jobs Syndrome (Hyper IgE Syndrome: HIES): Case Report and Literature Review.
Pak Paed J Jan ;45(4):484-6.

Jobs syndrome or hyper IgE syndrome is a heterogenous group of immunodeficiencies characterized by recurrent skin and pulmonary infections, high serum IgE levels (> 2000 IU/ml) and eczematous dermatitis. Other features involve coarse facial features and skeletal abnormalities. There are two types depending on the genes involved: autosomal dominant (AD-HIES) and autosomal recessive (AR-HIES). Approximately 250 cases of Jobs syndrome have been reported worldwide. Hereby we present a case of 2-year-old male child who presented to our hospital with cutaneous abscesses, dry skin and fever.

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