Sania Ashraf, Syed Najam Hyder, Usaid Ahmed, Munawer Ghous.
To Observe the Effect of Bi-ventricular Systolic and Diastolic Function in Neonates with Varying Degree of Pulmonary Hypertension.
Pak Paed J Jan ;45(4):439-43.

Objective: To evaluate bi-ventricular systolic and diastolic function in neonates with varying degree of pulmonary hypertension through echocardiography. Study Design: A cross-sectional study using convenience-sampling technique. Place and Duration of Study: Department of Pediatric Cardiology, The Children`s Hospital and the Institute of Child Health, Lahore from October 2019 for 6 months Material and Methods: We used a proforma as a data-collecting tool. The Institutional review board (IRB) and parent`s consent taken. All the data entered in SPSS version 25 and then analyzed for statistically significant outcomes. Descriptive analysis used to describe the basic features of the data through Pearson correlation. Results: Out of 73 patients, 63 were male and 10 were female. Mild pulmonary hypertension was present in 26% babies, moderate pulmonary hypertension detected in 24% babies and severe pulmonary hypertension detected in 49% neonates. Neonates with mild and moderate pulmonary hypertension showed 12% LV dysfunction while neonates with severe pulmonary hypertension 29% of these neonates had LV dysfunction. Neonates with mild pulmonary hypertension revealed that 36% had severe RV dysfunction and babies with moderate pulmonary hypertension 76% of them showed moderate to severe RV dysfunction. In category of severe pulmonary hypertension, 80% of babies were detected moderate to severe RV dysfunction. Conclusion: LV and RV dysfunction is significantly high with different degree of pulmonary hypertension in neonates. Hence, focus should made towards RV and LV function while evaluating these neonates for adequate management regarding pulmonary hypertension.

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