Anjum Saeed, Syeda Sara Batool, Zafar Fayyaz, Muhammad Nadeem Anjum, Nadia Waheed, Muhammad Arshad Alvi, Huma Arshad Cheema.
Etiology, Complications and Outcome in Pediatric Acute Pancreatitis.
Pak Paed J Jan ;45(4):434-8.

Objective: Acute pancreatitis (AP) in children is not an uncommon condition. In this study, we aimed to evaluate the etiology, complications and outcome for AP in children. Study Design: Prospective cross-sectional study. Place and Duration of Study: Department of Pediatric Gastroenterology & Hepatology, The Children`s Hospital & the Institute of Child Health, Lahore, Pakistan from January 2017 till January 2018. Material and Methods: 39 patients aged 2-16 years who fulfilled the INSPPIRE criteria for AP were included in the study. Patients having chronic or recurrent pancreatitis were excluded from the study. The data was entered and analyzed by SPSS version 23. Results: Of the 39 participants, 20 (51.2%) were females and 19 (48.8%) male with mean age of 7.97 +- 3.5 years. Abdominal pain and vomiting (97.4%) were the most common clinical features in these children. Eleven (28.2%) patients had idiopathic etiology, 9 (23%) had metabolic, 6 (15.3%) had hepatobiliary, 5 (12.8%) had infectious, 4 (10.2%) had traumatic, 2 (5.2%) had drug induced AP and 2 (5.2%) had systemic diseases causing AP. Pancreatic pseudocyst (30.7%) was the most common complication followed by hemorrhagic ascites (7.6%) & multi organ failure (7.6%). Twenty-four (61.5%) patients had mild AP, 9 (23%) had moderately severe AP and 6 (15.3%) severe AP. Majority of these children 36 (92.3%) recovered while three (7.7%) patients expired. Conclusion: Acute pancreatitis is not an uncommon condition in children. Abdominal pain and vomiting always need consideration for acute pancreatitis once more common causes are excluded. Early recognition and treatment of acute pancreatitis will help in appropriate treatment strategy.

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