Hafiz Abdul Quddus, Muhammad Naeem Farid, Lutfullah Goheer, Waseem Lehrasab, Hafiz Muhammad Murtaza, Samra Maryam.
Frequency of Acute Kidney Injury (AKI) in Neonates with Birth Asphyxia at a Tertiary Care Hospital.
Pak Paed J Jan ;46(1):3-8.

Objective: To determine the frequency of Acute Kidney Injury in perinatal asphyxia. Study Design: Cross-sectional study Place and Duration of Study: The Neonatal Intensive Care Unit, Pediatrics Department, Combined Military Hospital, Multan; from 26th August 2017 To 25th February 2018. Material and Methods: Total 120 patients were included with suspected birth asphyxia. Serum Lactate was sent within 30 min of birth. Blood samples were collected from the neonates at 24 hours of life and sent for serum creatinine analysis to ascertain acute kidney injury in these neonates. Results: There were 56.7% male and 43.3% female neonates. Mean gestational age was 38.05 +- 1.22 weeks. Mean 5 minutes APGAR score was 4.64 +- 1.32. Mean serum lactate and serum creatinine were 5.15 +- 0.63 mmol/L and 128.03 +- 6.17 umol/L respectively. Fetal distress on CTG was found in 47.5% cases while delayed cry was observed in 56.7% neonates. Most common grade of HIE was grade II in 57.55% neonates. Of these 120 patients, 13.3% neonates were found to have acute kidney injury. Conclusion: Current study demonstrates 13.3% AKI among patients with perinatal asphyxia. Gender, gestational age, and mode of delivery were found to have significant association with AKI.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com