Nauman Bari Khan, Simon Rawlinson, Pete Tomlins, Paul Anderson.
To study the effect of remineralisation on enamel using optical coherence tomography.
Pak Oral Dental J Jan ;41(4):227-31.

The aim of this research was to study the application of Optical coherence tomography (OCT) which could provide changes in degree of mineralization in tooth enamel. In vitro Study was planned at Dental Physical Sciences Unit, Barts & the London Institute of Dentistry. Six extracted teeth were taken for this part of the project which detected demineralize area using X-ray Microtomography (XMT) out of ten samples. These samples were then scanned using OCT to detect changes in remineralisation. For making the remineralising solution, the main ingredients used were calcium and phosphate and a pH of 7 was maintained for the remineralising solution. OCT was helpful in determining the remineralised areas in enamel. The average depth of penetration in the pre-mineralized zone was found to 11.27 +/- 7.5 um and when it was compared after the remineralized of the same site it was observed to be 6.39 +/-4.52 um and unpaired t-test value was <0.0001 suggesting a statistically significant result. OCT can detect and assess changes in degree of mineralization that are invisible to the eye. Development of the technique to allow chair-side diagnosis will permit early intervention to maintain oral and preserve whole body health.

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